Studies of Tritylated Sucrose. I. Mono-O-tritylsucroses

5'-O-tritylated nucleoside derivatives: inhibition of thymidine phosphorylase and angiogenesis.

Thymidine phosphorylase (TPase) is one of the key enzymes involved in the pyrimidine nucleoside salvage pathway. However, TPase also stimulates angiogenesis, and its expression correlates well with microvessel density and metastasis in a variety of human tumors. We have shown recently that 5'-O-trityl-inosine (KIN59) allosterically inhibits TPase enzymatic activity. KIN59 also inhibits TPase-in...

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The development of a recent technological product, referred to as Array of Conngurable Logic Cells, promotes many opportunities for research and implementationof digital circuits. These arrays include logic cells whose functions can be dynamically speciied by the user. The paper describes the main characteristics of conngurable cells, and indicates the potential use of these arrays for research...

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The relevance of security as one of the major contributors to an effective operational infrastructure has been growing in importance over the past 3-5 years, and today it resides as one of the two top investment priorities for senior management (the other one being critical server virtualization). Effective management by organizations when dealing with targeted and multiple parallel attacks com...

postnatal studies of bats (pipistrellus kuhlii and miniopterus schreibersii) & histomorphology and histochemistry studies of organs and diseases of (neurergus microspilotus and n. kaiseri)

1. to determine whether difference in birth body mass influenced growth performance in pipistrellus kuhlii we studied a total of 12 captive-born neonates. bats were assigned to two body mass groups: light birth body mass (lbw: 0.89 ± 0.05, n=8) and heavy birth body mass (hbw: 1.35 ± 0.08, n=4). heavier body mass at birth was associated with rapid postnatal growth (body mass and forearm length) ...